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Rapidly Degradable Amino-Functional Bis-MPA Dendrimers With Antibacterial Features



We are pleased to highlight a publication regarding the application of amino-functional bis-MPA dendrimers.

on regarding the application of amino-functional bis-MPA dendrimers.

We are pleased to highlight a publication regarding the application of amino-functional bis-MPA dendrimers.

We are pleased to highlight a publication regarding the application of amino-functional bis-MPA dendrimers.

“Synthesis and in Vitro Evaluation of Monodisperse Amino-Functional Polyester Dendrimers with Rapid Degradability and Antibacterial Properties. Stenström et. al. (2017). Biomacromolecules, 18, 12, 4323-4330.”

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In this paper, bis-MPA dendrimers were successfully decorated with multitude of amine and thereafter postfunctionalized in both organic as well as aqueous media. The amino-functional dendrimers were rapidly degraded under biologically relevant conditions. This class of dendrimers showed antibacterial properties that were highly promising in combination with low cyto-toxicity in relevant human cell lines.

More information about amino-functional dendrimers can be found here.


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