Polymer Factory's bis-MPA biotin-carboxyl dendrons are monodisperse, multifunctional scaffolds with 1 biotin focal point and an exact number of carboxylic acid surface groups. The carboxyl surface groups can be used for further coupling to amine containing molecules, while the biotin focal point allows conjugation to proteins through biotinylation and binding to streptavidin or avidin. Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.
1. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981
2. Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879
3. Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications - Prog. Pol. Sci., 2015, 48, 85-110
4. Fluoride-Promoted Esterification (FPE) Chemistry: A Robust Route to Bis-MPA Dendrons and Their Postfunctionalization - Molecules 2016, 21(3), 366
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