Product Description:
Polymer Factory's bis-MPA mPEG-COOH dendrons are multifunctional polyethylene glycol scaffolds with an exact number of carboxylic acid end groups. These materials feature a PEG core to aid water solubility and a high degree of functionality for each PEG chain. The carboxyl end groups can be used for coupling to amine-containing species via EDC/DCC coupling or NHS activation, generating highly functional materials. Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.
Publications:
1. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981
2. Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879
3. Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications - Prog. Pol. Sci., 2015, 48, 85-110
4. Linear Dendritic Block Copolymers as Promising Biomaterials for the Manufacturing of Soft Tissue Adhesive Patches Using Visible Light Initiated Thiol–Ene Coupling Chemistry - Adv. Funct. Mater., 2015, 25, 6596-6605
5. High-water-content mouldable hydrogels by mixing clay and a dendritic molecular binder - Nature, 2010, 463, 339-343
6. Combretastatin A-4 Conjugated Antiangiogenic Micellar Drug Delivery Systems Using Dendron–Polymer Conjugates - Mol. Phermaceutics, 2016, 13, 5, 1482-1490
7. Therapeutic Nanocarriers via Cholesterol Directed Self-Assembly of Well-Defined Linear-Dendritic Polymeric Amphiphiles - Chem. Mater., 2017, 29 (9), 3891–3898
bis-MPA Dendronised mPEG 10k, Carboxyl Functional Generation 1
- Type: PEG Linear Dendritic
- Core: PEG 10K
- Product Code : PFDO-011605
- End Group Functionality: Carboxyl
- Generation: 1
- Number of Surface Groups: 2
- Theoretical MW: g/mol
- bis-MPA = 2,2-bis(hydroxymethyl)propionic acid
- Form:
- Purity: >95%
- Delivery Time: 7-10 working days
- MSDS
- CoA Cover Sheet
- SOPs - EDC