Product Description:
Polymer Factory's bis-MPA mPEG-NHBOC dendrons are multifunctional polyethylene glycol scaffolds with an exact number of protected amine end groups. These materials feature a PEG core to aid water solubility and a high degree of functionality for each PEG chain.  After deprotection, the amine surface groups can be used for EDC/DCC coupling or coupling to NHS esters, generating highly functional materials.  Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.
 
Related Publications
 
Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981                               
Linear Dendritic Block Copolymers as Promising Biomaterials for the Manufacturing of Soft Tissue Adhesive Patches Using Visible Light Initiated Thiol–Ene Coupling Chemistry - Adv. Funct. Mater., 2015, 25, 6596-6605                                                                                                                                                                     
Synthesis and in Vitro Evaluation of Monodisperse Amino-Functional Polyester Dendrimers with Rapid Degradability and Antibacterial Properties -  Biomacromolecules, 2017, 18 (12), 4323-4330                                                                                                  
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications - Prog. Pol. Sci., 2015, 48, 85-110                                                                                                                                                  
Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879                                               
High-water-content mouldable hydrogels by mixing clay and a dendritic molecular binder - Nature, 2010, 463, 339-343                                                                                                 
Combretastatin A-4 Conjugated Antiangiogenic Micellar Drug Delivery Systems Using Dendron–Polymer Conjugates - Mol. Phermaceutics, 2016, 13, 5, 1482-1490                                                                                  
Therapeutic Nanocarriers via Cholesterol Directed Self-Assembly of Well-Defined Linear-Dendritic Polymeric Amphiphiles - Chem. Mater., 2017, 29 (9), 3891–3898                                                                                        
Evaluation of Amino-Functional Polyester Dendrimers Based on Bis-MPA as Nonviral Vectors for siRNA Delivery - Molecules, 2018, 23 (8), 2028