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Product Description:

Polymer Factory's bis-MPA Acetylene-OH dendrons are monodisperse, multifunctional scaffolds with 1 alkyne focal point and an exact number of hydroxyl surface groups. The acetylene focal point can be used for click chemistry conjugation such as CuAAC and thiol-yne coupling to produce highly functional materials.   Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.


Related Publications


  1. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981                                                                           
  2. Multivalent, bifunctional dendrimers prepared by click chemistryChem. Comm., 2005, 0, 5775-5777                                     
  3. Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879                                                                              
  4. Structurally Diverse Dendritic Libraries:  A Highly Efficient Functionalization Approach Using Click ChemistryMacromolecules, 2005, 38 (9), 3663-3678                                                                                                                           
  5. Fluoride-Promoted Esterification (FPE) Chemistry: A Robust Route to Bis-MPA Dendrons and Their Postfunctionalization - Molecules, 2016, 21(3), 366                                                                              
  6. Fluoride‐Promoted Esterification with Imidazolide‐Activated Compounds: A Modular and Sustainable Approach to DendrimersAngew. Chem. Int. Ed., 2015, 54, 2416-2419