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Product Description:

Polymer Factory's bis-MPA carboxyl-hydroxyl dendrons are monodisperse, multifunctional scaffolds with 1 carboxylic acid focal point and an exact number of hydroxyl surface groups. The carboxyl focal point can be used for conjugation to amine containing materials via EDC/DCC or coupling to NHS-esters. Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.


Related Publications


  1. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981                               
  2. Fluoride-Promoted Esterification (FPE) Chemistry: A Robust Route to Bis-MPA Dendrons and Their Postfunctionalization - Molecules, 2016, 21(3), 366                       
  3. Fluoride‐Promoted Esterification with Imidazolide‐Activated Compounds: A Modular and Sustainable Approach to Dendrimers -  Macromolecules, 2005, 38 (9), 3663-3678                                                                                                                                                   
  4. Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879                                                        

bis-MPA Hydroxyl Dendron, Carboxyl Core, Generation 3

SKU: PFDO-030501