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Product Description:

Polymer Factory's bis-MPA Acetylene-NHBOC dendrons are monodisperse, multifunctional scaffolds with 1 alkyne focal point and an exact number of protected amine surface groups. After deprotection, the amine surface groups can be used for EDC/DCC coupling or coupling to NHS esters, while the acetylene focal point can be used for click chemistry conjugation such as CuAAC and thiol-yne coupling, to yield highly functional materials.   Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.


Related Publications


  1. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981                               
  2. Multivalent, bifunctional dendrimers prepared by click chemistry - Chem. Comm., 2005, 0, 5775-5777                         
  3. Structurally Diverse Dendritic Libraries:  A Highly Efficient Functionalization Approach Using Click Chemistry -  Macromolecules, 2005, 38 (9), 3663-3678