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Product Description:

Polymer Factory's bis-MPA carboxyl-NHBOC dendrons are monodisperse, multifunctional scaffolds with 1 carboxylic acid focal point and an exact number of protected amine surface groups. After deprotection, the amine surface groups can be used for EDC/DCC coupling or coupling to NHS esters,  while the carboxyl focal point can be used for further coupling to amine containing materials.   Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.


Related Publications


  1. Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981                                                                           
  2. Synthesis and in Vitro Evaluation of Monodisperse Amino-Functional Polyester Dendrimers with Rapid Degradability and Antibacterial Properties Biomacromolecules, 2017, 18 (12), 4323-4330                                           
  3. Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879                                                                              
  4. Evaluation of Amino-Functional Polyester Dendrimers Based on Bis-MPA as Nonviral Vectors for siRNA Delivery -  Molecules, 2018, 23 (8), 2028


bis-MPA NHBoc Dendron, Carboxyl Core, Generation 1

SKU: PFDO-010513