Polymer Factory’s first ESI-designated calibration kit is based on hydrophilic dendritic macromolecules that cover the mass range between 295 and 1,550 Da.
 
We are now offering this product as a pre-launch at small portion size of 5 µg at a beneficial price. Since we are eager to learn about the performance of our product on various platforms and under varying conditions, we offer further discounts for future orders of the fully released product in exchange for your feedback and shared data (spectra, spraying conditions, etc.).
 
What makes SpheriCal® ESI unique?
In contrast to other calibration solutions, we offer our calibrants as solid, neat compound. The material is fully soluble in hydrophilic solvents commonly used in ESI. This includes water, alcohols, aqueous mixtures of alcohols, aqueous ACN.
Our compounds are “non-sticky” in the ion source and will not tail into your data. At the same time, the compatibility with a wide range of spraying solutions and conditions enables internal calibration.
Further, SpheriCal® does not contain any fluorinated components.
With a shelf life of years, we expect the 5 µg portions to enable about 100 calibrations.
SpheriCal® offers reliable and accurate calibration, without the shelf-life and storage issues associated with protein or peptide-based systems. Simply freeze your aliquots once prepared.
 
In positive mode, our compounds do not need addition of acetic or formic acid and ionize well with traces of Na to yield [M+Na]+. Addition of acid will also yield [M+H]+ in positive mode.
In negative mode, addition of acid is required and yields [M+acid-H]- anions. [M-H]- might also be observed.
This gives full control to the end user to choose concentration, solvent, addition of acid etc.
 
Componets:
C6H12O4; 148.074 g/mol*
C12H22O8; 294.131 g/mol
C20H36O12; 468.221 g/mol
C25H44O16; 600.623 g/mol
C30H52O20; 732.305 g/mol
C37H62O22; 858.373 g/mol
C40H70O25; 950.421 g/mol
C50H84O30; 1,164.505 g/mol
C65H108O40; 1,528.642 g/mol
 
*Compound 1 varies in intensity depending on hardware and tuning and is not guaranteed to be detectable.
 
 
Related Publications
              
Advantages of Monodisperse and Chemically Robust “SpheriCal” Polyester Dendrimers as a “Universal” MS Calibrant - J. Am. Soc. Mass Spectrom., 2014, 25, 303-309