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Bis-MPA dendritic scaffolds are used to create high mass (up to 66 kDa) monodisperse PEGylated dendrimers with a range of functional handles. Poly(ethylene glycol) (PEG) is an attractive platform for a range of biomedical and pharmaceutical applications due to the low immunogenicity, antigenicity and toxicity. In particular, PEGylation of bioactive molecules is pursued in order to improve solubility in biological media and extend the circulation time after a drug is administe

Dual drug delivery system using linear dendritic polymeric nanocarriers to enhance therapeutic efficacy towards drug-resistant cancer cells.